Reflect: Rectified Flows for Efficient Brain Anomaly Correction Transport

Research output: Contribution to Book/Report typesContribution to conference proceedingspeer-review

Abstract

Unsupervised anomaly detection (UAD) in brain imaging is crucial for identifying pathologies without the need for labeled data. However, accurately localizing anomalies remains challenging due to the intricate structure of brain anatomy and the scarcity of abnormal examples. In this work, we introduce Reflect, a novel framework that leverages rectified flows to establish a direct, linear trajectory for correcting abnormal MR images toward a normal distribution. By learning a straight, one-step correction transport map, our method efficiently corrects brain anomalies and can precisely localize anomalies by detecting discrepancies between anomalous input and corrected counterpart. In contrast to the diffusion-based UAD models, which require iterative stochastic sampling, rectified flows provide a direct transport map, enabling single-step inference. Extensive experiments on popular UAD brain segmentation benchmarks demonstrate that Reflect significantly outperforms state-of-the-art unsupervised anomaly detection methods. The code is available at https://github.com/farzad-bz/REFLECT.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention, MICCAI 2025 - 28th International Conference, Proceedings
EditorsJames C. Gee, Jaesung Hong, Carole H. Sudre, Polina Golland, Daniel C. Alexander, Juan Eugenio Iglesias, Archana Venkataraman, Jong Hyo Kim
PublisherSpringer Science and Business Media Deutschland GmbH
Pages456-466
Number of pages11
ISBN (Print)9783032049643
DOIs
Publication statusPublished - 2026
Event28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025 - Daejeon, South Korea
Duration: 23 Sept 202527 Sept 2025

Publication series

NameLecture Notes in Computer Science
Volume15963 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025
Country/TerritorySouth Korea
CityDaejeon
Period23/09/2527/09/25

!!!Keywords

  • Brain MRI
  • Rectified flows
  • Unsupervised anomaly detection

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