TY - GEN
T1 - Reflect
T2 - 28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025
AU - Beizaee, Farzad
AU - Hajimiri, Sina
AU - Ben Ayed, Ismail
AU - Lodygensky, Gregory
AU - Desrosiers, Christian
AU - Dolz, Jose
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2026.
PY - 2026
Y1 - 2026
N2 - Unsupervised anomaly detection (UAD) in brain imaging is crucial for identifying pathologies without the need for labeled data. However, accurately localizing anomalies remains challenging due to the intricate structure of brain anatomy and the scarcity of abnormal examples. In this work, we introduce Reflect, a novel framework that leverages rectified flows to establish a direct, linear trajectory for correcting abnormal MR images toward a normal distribution. By learning a straight, one-step correction transport map, our method efficiently corrects brain anomalies and can precisely localize anomalies by detecting discrepancies between anomalous input and corrected counterpart. In contrast to the diffusion-based UAD models, which require iterative stochastic sampling, rectified flows provide a direct transport map, enabling single-step inference. Extensive experiments on popular UAD brain segmentation benchmarks demonstrate that Reflect significantly outperforms state-of-the-art unsupervised anomaly detection methods. The code is available at https://github.com/farzad-bz/REFLECT.
AB - Unsupervised anomaly detection (UAD) in brain imaging is crucial for identifying pathologies without the need for labeled data. However, accurately localizing anomalies remains challenging due to the intricate structure of brain anatomy and the scarcity of abnormal examples. In this work, we introduce Reflect, a novel framework that leverages rectified flows to establish a direct, linear trajectory for correcting abnormal MR images toward a normal distribution. By learning a straight, one-step correction transport map, our method efficiently corrects brain anomalies and can precisely localize anomalies by detecting discrepancies between anomalous input and corrected counterpart. In contrast to the diffusion-based UAD models, which require iterative stochastic sampling, rectified flows provide a direct transport map, enabling single-step inference. Extensive experiments on popular UAD brain segmentation benchmarks demonstrate that Reflect significantly outperforms state-of-the-art unsupervised anomaly detection methods. The code is available at https://github.com/farzad-bz/REFLECT.
KW - Brain MRI
KW - Rectified flows
KW - Unsupervised anomaly detection
UR - https://www.scopus.com/pages/publications/105017853208
U2 - 10.1007/978-3-032-04965-0_43
DO - 10.1007/978-3-032-04965-0_43
M3 - Contribution to conference proceedings
AN - SCOPUS:105017853208
SN - 9783032049643
T3 - Lecture Notes in Computer Science
SP - 456
EP - 466
BT - Medical Image Computing and Computer Assisted Intervention, MICCAI 2025 - 28th International Conference, Proceedings
A2 - Gee, James C.
A2 - Hong, Jaesung
A2 - Sudre, Carole H.
A2 - Golland, Polina
A2 - Alexander, Daniel C.
A2 - Iglesias, Juan Eugenio
A2 - Venkataraman, Archana
A2 - Kim, Jong Hyo
PB - Springer Science and Business Media Deutschland GmbH
Y2 - 23 September 2025 through 27 September 2025
ER -