TY - GEN
T1 - SimCortex
T2 - International Workshop on Shape in Medical Imaging, ShapeMI 2025, Held in Conjunction with the 28th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2025
AU - Moradkhani, Kaveh
AU - Rushmore, R. Jarrett
AU - Bouix, Sylvain
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2026.
PY - 2026
Y1 - 2026
N2 - Accurate cortical surface reconstruction from magnetic resonance imaging (MRI) data is crucial for reliable neuroanatomical analyses. Current methods have to contend with complex cortical geometries, strict topological requirements, and often produce surfaces with overlaps, self-intersections, and topological defects. To overcome these shortcomings, we introduce SimCortex, a deep learning framework that simultaneously reconstructs all brain surfaces (left/right white-matter and pial) from T1-weighted(T1w) MRI volumes while preserving topological properties. Our method first segments the T1w image into a nine-class tissue label map. From these segmentations, we generate subject-specific, collision-free initial surface meshes. These surfaces serve as precise initializations for subsequent multiscale diffeomorphic deformations. Employing stationary velocity fields (SVFs) integrated via scaling-and-squaring, our approach ensures smooth, topology-preserving transformations with significantly reduced surface collisions and self-intersections. Evaluations on standard datasets demonstrate that SimCortex dramatically reduces surface overlaps and self-intersections, surpassing current methods while maintaining state-of-the-art geometric accuracy.
AB - Accurate cortical surface reconstruction from magnetic resonance imaging (MRI) data is crucial for reliable neuroanatomical analyses. Current methods have to contend with complex cortical geometries, strict topological requirements, and often produce surfaces with overlaps, self-intersections, and topological defects. To overcome these shortcomings, we introduce SimCortex, a deep learning framework that simultaneously reconstructs all brain surfaces (left/right white-matter and pial) from T1-weighted(T1w) MRI volumes while preserving topological properties. Our method first segments the T1w image into a nine-class tissue label map. From these segmentations, we generate subject-specific, collision-free initial surface meshes. These surfaces serve as precise initializations for subsequent multiscale diffeomorphic deformations. Employing stationary velocity fields (SVFs) integrated via scaling-and-squaring, our approach ensures smooth, topology-preserving transformations with significantly reduced surface collisions and self-intersections. Evaluations on standard datasets demonstrate that SimCortex dramatically reduces surface overlaps and self-intersections, surpassing current methods while maintaining state-of-the-art geometric accuracy.
KW - 3D Deep Learning
KW - Brain MRI
KW - Brain Segmentation
KW - Cortical Surface Reconstruction
KW - Geometric Deep Learning
UR - https://www.scopus.com/pages/publications/105020011562
U2 - 10.1007/978-3-032-06774-6_26
DO - 10.1007/978-3-032-06774-6_26
M3 - Contribution to conference proceedings
AN - SCOPUS:105020011562
SN - 9783032067739
T3 - Lecture Notes in Computer Science
SP - 347
EP - 359
BT - Shape in Medical Imaging - International Workshop, ShapeMI 2025, Held in Conjunction with MICCAI 2025, Proceedings
A2 - Wachinger, Christian
A2 - Luijten, Gijs
A2 - Egger, Jan
A2 - Elhabian, Shireen
A2 - Gopinath, Karthik
PB - Springer Science and Business Media Deutschland GmbH
Y2 - 23 September 2025 through 23 September 2025
ER -