Pharmaceutical supply chains face different kind of risks and uncertainties and managing the risks has emerged as an important issue with constantly changes in the supply chain. To successfully manage the risks, it is important to identify risks and uncertainties and know how to mitigate these risks with proper risk mitigation strategy. The purpose of this study is to investigate the existing literature to identify risks and risks mitigation strategies by using Text-Mining techniques instead of traditional literature review approach.
The methods we applied to perform a Systematic Literature Review (SLR) consist of phrase extraction by lexical approach and using Natural Language Toolkit (NLTK), semantic similarity clustering (include vectorizing by Universal Sentence Encoder method and similarity matrix method), and post-processing.
A total 4205 papers were extracted after applying related search strings in the three search engines of Web of Science, PubMed, and Google Scholar. At last, after performing different phases of removing duplicated references, title screening, and title and abstract screening in the DistillerSR software, 278 references formed our project's selected studies.
The results demonstrate that 317 risks in general are identified in 24 different groups of products, logistics, material, supply, financial, drug, customer, technological, inventory, regulatory/legislation, information, demand, cost, transportation, market, quality, political, environmental, human, organization, international, network, technical, operational, and other. Top three risks that are discussed the most in the literature include supply risks, operational risks, and quality risks respectively. Top four groups with more risks are supply, product, transportation, and financial having 27, 27, 22, and 20 risks respectively. moreover, more than 73 risk mitigation strategies are found in the literature that targeted different risks in the field of capacity, clinical trial, compliance, customer service, supply, demand, etc. Different studies have worked on the problem of shortages in drugs and medicines. The second risk that has received the most attention from researchers is supply-related risks.
| Date | 10 Dec 2021 |
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| Original language | American English |
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| Awarding Institution | - École de technologie supérieure
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| Supervisor | Yvan Beauregard (Supervisor) |
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