A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution: A powerful tool for carbohydrate synthesis

Milan Bergeron-Brlek; Timothy Teoh; Robert Britton

doi:10.1021/ol401370b

A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution: A powerful tool for carbohydrate synthesis

Milan Bergeron-Brlek
, Timothy Teoh
, Robert Britton

Simon Fraser University

Résultats de recherche: Contribution à un journal › Article publié dans une revue, révisé par les pairs › Revue par des pairs

57 Citations (Scopus)

Résumé

A tandem, proline-catalyzed α-chlorination/aldol reaction is described that involves a dynamic kinetic resolution of α-chloroaldehyde intermediates. The resulting syn-chlorohydrins are produced with good to excellent diastereoselectivity in high enantiopurity and provide new opportunities for the synthesis of carbohydrates.

langue originale	Anglais
Pages (de - à)	3554-3557
Nombre de pages	4
journal	Organic Letters
Volume	15
Numéro de publication	14
Les DOIs	https://doi.org/10.1021/ol401370b
état	Publié - 19 juil. 2013
Modification externe	Oui

Accès au document

10.1021/ol401370b

Autres fichiers et liens

Lien vers la publication dans Scopus

Empreinte digitale

Voici les principaux termes ou expressions associés à « A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution: A powerful tool for carbohydrate synthesis ». Ces libellés thématiques sont générés à partir du titre et du résumé de la publication. Ensemble, ils forment une empreinte digitale unique.

Contient cette citation

@article{c984ab83af8f4d1aa00b2933229fd803,

title = "A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution: A powerful tool for carbohydrate synthesis",

abstract = "A tandem, proline-catalyzed α-chlorination/aldol reaction is described that involves a dynamic kinetic resolution of α-chloroaldehyde intermediates. The resulting syn-chlorohydrins are produced with good to excellent diastereoselectivity in high enantiopurity and provide new opportunities for the synthesis of carbohydrates.",

author = "Milan Bergeron-Brlek and Timothy Teoh and Robert Britton",

year = "2013",

month = jul,

day = "19",

doi = "10.1021/ol401370b",

language = "English",

volume = "15",

pages = "3554--3557",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "14",

}

A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution: A powerful tool for carbohydrate synthesis. / Bergeron-Brlek, Milan; Teoh, Timothy; Britton, Robert.
Dans: Organic Letters, Vol 15, Numéro 14, 19.07.2013, p. 3554-3557.

Résultats de recherche: Contribution à un journal › Article publié dans une revue, révisé par les pairs › Revue par des pairs

TY - JOUR

T1 - A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution

T2 - A powerful tool for carbohydrate synthesis

AU - Bergeron-Brlek, Milan

AU - Teoh, Timothy

AU - Britton, Robert

PY - 2013/7/19

Y1 - 2013/7/19

N2 - A tandem, proline-catalyzed α-chlorination/aldol reaction is described that involves a dynamic kinetic resolution of α-chloroaldehyde intermediates. The resulting syn-chlorohydrins are produced with good to excellent diastereoselectivity in high enantiopurity and provide new opportunities for the synthesis of carbohydrates.

AB - A tandem, proline-catalyzed α-chlorination/aldol reaction is described that involves a dynamic kinetic resolution of α-chloroaldehyde intermediates. The resulting syn-chlorohydrins are produced with good to excellent diastereoselectivity in high enantiopurity and provide new opportunities for the synthesis of carbohydrates.

UR - https://www.scopus.com/pages/publications/84880562104

U2 - 10.1021/ol401370b

DO - 10.1021/ol401370b

M3 - Journal Article

C2 - 23819733

AN - SCOPUS:84880562104

SN - 1523-7060

VL - 15

SP - 3554

EP - 3557

JO - Organic Letters

JF - Organic Letters

IS - 14

ER -